1-(1-Adamantylcarbonyl)proline (ACA), Purity 99% Min, 5g/10g, CAS 35084-48-1

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Product introduction

 1-(1-Adamantylcarbonyl) proline is a phenylalanine derivative, also known as adamantylproline or Ad-Pro. Mainly used as catalyst or chiral resolution reagent in organic synthesis. Studies have shown that 1-(1-Adamantylcarbonyl) proline can catalyze asymmetric nucleophilic addition reactions, such as the reaction of aldehydes and alkylene azides, the reaction of aldehydes and sulfuryl folate, the reaction of aldehydes and nitro Methane reactions, etc. Among these reactions, this catalyst has the strongest addition activity toward alkylene azides.  1-(1-Adamantylcarbonyl) proline can also catalyze asymmetric amination reactions.  1-(1-Adamantylcarbonyl) proline can also be used as a chiral catalyst to catalyze asymmetric alcoholization. For example, it can react alcohols with aldehydes or ketones to yield the corresponding aldol or hydroxyketone products.  1-(1-Adamantylcarbonyl) proline, as a chiral organic compound, has excellent catalytic activity.

Features

 (1)1-(1-Adamantylcarbonyl) proline is a white or off-white powder with good solubility. It has low solubility in water but often has good solubility in organic solvents. It is a stable compound that can be stored at room temperature for long periods of time.

 (2) 1-(1-Adamantylcarbonyl) proline is a chiral molecule with two enantiomers. Its chiral nature makes it widely used in chiral synthesis. Generally, only one chiral isomer should be used because of its good chiral induction.
(3) High purity: 1-(1-Adamantylcarbonyl) proline can obtain high-purity products through natural extraction and refining production processes. High purity means better bioavailability and fewer adverse reactions.
(4) Stability: 1-(1-Adamantylcarbonyl) proline has good stability and can maintain its activity and effect under different environments and storage conditions.

Application areas

 1-(1-Adamantylcarbonyl) proline is a nitrogen-containing organic compound, white or off-white powder, used as an intermediate and other applications in medicine. In addition, due to its unique chiral properties, it is widely used in chiral organic synthesis, including asymmetric nucleophilic addition reactions, amination reactions, alcoholization reactions, etc.